Select Publications

Structure of Protein Related to Dan and Cerberus (PRDC).
Nolan, K.; Kattamuri, C.; Luedeke, D.M.; Jagpal, A.; Zhang, F.; Linhardt, R.; Kenny, A.P.; Zorn, A.M.; Thompson, T.B., Structure of protein related to dan and cerberus: insights into the mechanism of bone morphogenetic protein antagonism. Structure 2013, 21, (8), 1417-29.
(Pub Med) PDB: 4JPH

DAN Family Antagonists Exist as Noncovalent Dimers.
Kattamuri, C.; Luedeke, D.M.; Nolan, K.; Rankin, S.A.; Greis, A.; Zorn, A.M.; Thompson, T.B., Members of the dan family are BMP antagonists that form highly stable noncovalent dimers. J Mol Bio 2012, 424, (5), 313-27.
(Pub Med)

Analysis of Heparin-Follistatin Binding and Interactions.
Zhang, F.; Beaudet, J.M.; Luedeke, D.M.; Walker, R.G.; Thompson, T.B.; Linhardt, R.J., Analysis of the interaction between heparin and follistatin and heparin and follistatin-ligand complexes using surface plasmon resonance. Biochemistry 2012, 51, (34), 6797-803.
(Pub Med)

Contribution of Follistatin's Domains towards Antagonism.
Cash, J.N.; Angerman, E.B.; Keutmann, H.T.; Thompson, T.B., Characterization of follistatin-type domains and their contribution to myostatin and activin A antagonism. Mol Endocrinol 2012, 26, (7), 1167-78.
(Pub Med)

Purification of PRDC.
Kattamuri, C.; Luedeke, D.M.; Thompson, T.B., Expression and purification of recombinant protein related to DAN and cerberus (PRDC).Protein Expr Purif 2012, 82, (2), 389-95.
(Pub Med)

Myostatin in Complex with FSTL3.
Cash, J.N.; Angerman, E.B.; Kattamuri, C.; Nolan, K.; Zhao, H.; Sidis, Y.; Keutmann, H.T.; Thompson, T. B., Structure of myostatin:follistatin-like 3: N-terminal domains of follistatin-type molecules exhibit alternate modes of binding. J Biol Chem 2012, 287, (2), 1043-53.
(Pub Med) PDB: 3SEK

Myostatin in Complex with FST288.
Cash, J.N.; Rejon, C.A.; McPherron, A.C.; Bernard, D.J.; Thompson, T. B., The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding. Embo J 2009, 28, (17), 2662-76.
(Pub Med) PDB: 3HH2

Activin in Complex with FSTL3.
Stamler, R.; Keutmann, H. T.; Sidis, Y.; Kattamuri, C.; Schneyer, A.; Thompson, T. B., The structure of FSTL3:activin a complex: differential binding of N-terminal domains influences follistatin-type antagonist specificity. J Biol Chem 2008, 283, (47), 32831-8.
(Pub Med) PDB: 3B4V

Activin in Complex with FST288 (Northwestern University).
Thompson, T. B.; Lerch, T. F.; Cook, R. W.; Woodruff, T. K.; Jardetzky, T. S., The structure of the follistatin:activin complex reveals antagonism of both type I and type II receptor binding. Dev Cell 2005, 9, (4), 535-43.
(Pub Med) PDB: 2B0U

SAXS of Apolipoprotein A-IV Reveals Importance of Termini.
Deng X.; Morris J.; Chaton, C.; Schroder, G.F.; Davidson, W.S.; Thompson T.B., Small-angle X-ray scattering of apolipoprotein A-IV reveals the importance of its termini for structural stability.J Biol Chem 2013, 288, (7), 4854-66.
(Pub Med)

Structure of Apolipoprotein A-IV.
Deng, X.; Morris, J.; Dressmen, J.; Tubb, M.R.; Tso, P.; Jerome, W.G.; Davidson, W.S.; Thompson, T. B., The structure of dimeric apolipoprotein A-IV and its mechanism of self-association. Structure 2012, 20, (5), 767-79.
(Pub Med) PDB: 3S84

Dehydration and Diffraction of Apolipoprotein A-IV Crystals.
Deng X.; Davidson W.S.; Thompson, T.B., Improving the diffraction of apoA-IV crystals through extreme dehydration.Acta Crystallogr Sect F Struct Biol Cryst Commun 2012, 68, (Pt 1), 105-10.
(Pub Med)

Other publications from Dr. Tom Thompson.